Thank you to Professor Ronald Krauss for joining me today to talk about cholesterol. Professor Krauss is a pioneering lipidologist who has changed the way we all think about cholesterol and how to measure it. He has also done a lot of research on how different foods affect our cholesterol levels.

Professor Krauss has over 470 published papers and has conducted a number of clinical trials and other research projects that focus on how plasma lipoproteins and other traits influence the risk of coronary artery disease.

In our discussion Professor Krauss explains in layman’s terms what is measured on the cholesterol tests we get from the GP. He explains the role of cholesterol in the body and the difference between cholesterol and the lipoproteins transporters (LDL and HDL) that carry cholesterol and other lipids around our blood stream. He talks about the different factors that affect these, such as diet and genetics.

He describes the newer types of tests that can differentiate between the larger more buoyant (less dangerous LDL-particles) and the smaller more atherogenic particles that are more easily oxidised and able to get into the artery wall.

We discuss his research into the dietary causes of increased small LDL particles and why cholesterol panels need careful interpreting based on a variety of factors.

Metabolic syndrome is diagnosed with three or more of the following symptoms is a high risk for heart disease as we age.

– High blood pressure
– High triglycerides
– High waist to height ratio
– Low HDL

Diet and lifestyle changes can reduce this risk substantially.

Dr Krauss also explains about the nuances in identifying cardiovascular risk and when statin prescriptions are appropriate. He believes many people are taking these drugs unnecessarily, while others are not taking them who would benefit. He discusses his research into the side effects, particularly muscle pain and an increased risk of type-2 diabetes.

I appreciate Professor Krauss taking the time to talk with me today – it was a privilege to have him join the podcast.

He does offer telemedicine consultations for those wishing to have an in-depth look at their risk factors for cardiovascular disease. He can be emailed at ccmh@jumpstartmd.com

Website: https://profiles.ucsf.edu/ronald.krauss